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Scientists at Johns Hopkins’ Bloomberg~Kimmel Institute for Cancer Immunotherapy, have uncovered a key missing link between a common gut bacterium and colorectal cancer, according to an October 31, 2026 Science Daily report. The bacterium, Bacteroides fragilis (BHT), produces a toxin that damages the colon’s protective lining.
Researchers have uncovered the missing step, a protein called claudin-4 that serves as an essential docking point for toxins showing new ways to protect the colon.
BHT is found in up to 20% of healthy people. However, certain strains (not all) of BHT produce a powerful toxin capable of “disrupting the colon’s protective lining, causing inflammation, and encouraging tumor growth,” says the Science Daily report.
https://www.sciencedaily.com/releases/2026/10/261031012912.htm
Herbsprout is a blog and podcast about the health benefits of our gut microbiome, natural remedies, and healthcare innovations. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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