Researchers from Finland and Norway found two compounds with strong antivirulence or antibacterial effects against (enteropathogenic) E. coli by screening for actinobacteria living inside invertebrates in the Arctic Sea.
Research of actinobacteria in other habitats is promising. 70% of all currently licensed antibiotics have been derived from actinobacteria in the soil, and most environments on Earth have not yet been prospected for them.
In this case, researchers found compounds in the Arctic Ocean. This is where Dr Päivi Tammela, a professor at the University of Helsinki, Finland, and her team discovered a compound that restricts enteropathogenic E. coli (EPEC) virulence without affecting its growth, according to a Frontiers August 29 2024 report. The use of antivirulent compounds leads many to believe this may end the struggle to find stronger and stronger antibiotics.
https://www.instagram.com/reel/DOKpO77Dh8j/?igsh=MW9xbTEzbHp0N29laA==
https://www.frontiersin.org/news/2024/08/30/promising-antibiotic-candidates-discovered-in-microbes-deep-in-the-arctic
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