While fecal sampling is the current standard for representing the whole human gut microbiome, fecal microbiome is insufficient to represent the whole gut microbiome of the GI tract in a recent study of pigs, according to Hindawa Cellular Biology January 17 2023 issue.
For one, stool consistency varies over time. In addition, both gut microbiome composition and phenotypes or diseases of interest help define the nature of one’s health. Researchers then found a significant compositional difference of gut microbiome by specific location along the GI tract. All this calls for greater accuracy than exclusively using stool samples as a means for determining gut health and gut research.
https://www.hindawi.com/journals/cmi/2023/6868417/
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