The intake of compounds such as nanoparticles impacts our gut microbiota balance, changing gut composition everyday which in turn, influences our physiological process. A recent study shows that our gut microbiota is able to break down carbon nanomaterials into organic metabolites, according to a May 19 2023 Phys.org report. What is the result of this fermentation process? The short answer is “short chain fatty acids” (SCFAs).
Prof. Chen Chunying from the National Center for Nanoscience and Technology (NCNST) of the Chinese Academy of Sciences (CAS) showed that gut microbiota can ferment carbon nanomaterials (CNMs) as carbon sources into SCFAs.
Specifically, researchers found in mice studies a “variety of microbial enzymes, including hexokinase, pyruvate kinase, pyruvate dehydrogenase and butyrate kinase” which were involved in fermenting CNMs into butyrate.
It is a serendipitous discovery, given that gut microbes can ferment synthetics previously perceived as potentially harmful into something potentially useful to our bodies. However, a Cambridge report based on a number of European studies cautions that “effects on NPs agglomeration and aggregation are still unknown”.
https://phys.org/news/2023-05-reveals-gut-microbiota-ferment-carbon.pdf
https://www.cambridge.org/core/journals/gut-microbiome/article/intake-of-nanoparticles-and-impact-on-gut-microbiota-in-vitro-and-animal-models-available-for-testing/BAECA0F1AA93D5806648F06A2254B183#
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